Watson and crick dna research paper


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DNA double helix: how James Watson and Francis Crick cracked the secret of life

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The molecule of life

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The relationship between Wilkins and Franklin was unfortunately a poor one and probably slowed their progress. He had worked under Salvador E. Luria at Indiana on bacteriophages, the viruses that invade bacteria in order to reproduce—a topic for which Luria received a Nobel Prize in Physiology or Medicine in Watson went to Denmark for postdoctoral work, to continue studying viruses and to remedy his relative ignorance of chemistry.

He was hooked.


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To request permission to use this photo, please visit the Science Photo Library website at www. Watson soon moved to the Cavendish Laboratory, where several important X-ray crystallographic projects were in progress. Under the leadership of William Lawrence Bragg, Max Perutz was investigating hemoglobin and John Kendrew was studying myoglobin, a protein in muscle tissue that stores oxygen. Perutz and Kendrew received the Nobel Prize in Chemistry for their work in the same year that the prize was awarded to the DNA researchers— Crick, another physicist in biology, was supposed to be writing a dissertation on the X-ray crystallography of hemoglobin when Watson arrived, eager to recruit a colleague for work on DNA.

The four scientists announced the structure of DNA in articles that appeared together in the same issue of Nature.

Watson and Crick's Nature paper, Arthur Kornberg

The problem was that he was unsure what he did want to do. In the end, he decided to enter the life sciences. He liked reading, thinking, and talking about the new discoveries being made in the life sciences.

The discovery of DNA | Stories | pecheckrirollpas.ml

Crick found that "what you are really interested in is what you gossip about. He finally settled in for a two year stint at Strangeways Laboratory where he did work on the effects of magnetism on chick fibroblast cells. Sir Lawrence Bragg was directing a new unit of the Laboratory where they were using X-ray crystallography to study protein structure. Max Perutz was working on the structure of hemoglobin and Crick's thesis project was on X-ray diffraction of proteins.

Watson and Crick discover chemical structure of DNA

Although Crick was twelve years older, he and Watson "hit it off immediately. The classic paper was published in Nature in April A flip of the coin decided the order of the names on the paper. Maurice Wilkins and Rosalind Franklin provided some of the X-ray crystallographic data. After the "double helix" model, there were still questions about how DNA directed the synthesis of proteins.

Crick and some of his fellow scientists, including James Watson, were members of the informal "RNA tie club," whose purpose was "to solve the riddle of RNA structure, and to understand the way it builds proteins.

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